Figure 1
Figure 1. Deletion of Slug does not disturb homeostasis of primitive hematopoietic cells in BM of mice. (A) The frequencies of LSK cells, Flk2− LSK HSCs, SLAM (CD150− CD48+ CD244+) HSCs, and EPCR+ HSCs as a percentage of total BM mononuclear cells in Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). (B) The percentage of MPP (CD150−CD48−CD244+) and LRPs (CD150−CD48+CD244+) in BM of Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). (C) The frequencies of Ki-67+ cells in LSK cell populations in Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). (D) The frequencies of T, B, and myeloid cells in Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). Data shown were the mean ratio ± SD. There is no significant difference for each type of cells in Slug+/+ mice vs Slug+/− mice vs Slug−/− mice.

Deletion of Slug does not disturb homeostasis of primitive hematopoietic cells in BM of mice. (A) The frequencies of LSK cells, Flk2− LSK HSCs, SLAM (CD150− CD48+ CD244+) HSCs, and EPCR+ HSCs as a percentage of total BM mononuclear cells in Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). (B) The percentage of MPP (CD150−CD48−CD244+) and LRPs (CD150−CD48+CD244+) in BM of Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). (C) The frequencies of Ki-67+ cells in LSK cell populations in Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). (D) The frequencies of T, B, and myeloid cells in Slug+/+ mice (n = 5), Slug+/− mice (n = 5), and Slug−/− mice (n = 5). Data shown were the mean ratio ± SD. There is no significant difference for each type of cells in Slug+/+ mice vs Slug+/− mice vs Slug−/− mice.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal