Detection of serum paraproteins in sera of PCT-bearing mice. (A) Sera are from C.IL6/iMyc primary PCT (G0 samples) or tumor cell transplant recipients (G1 samples). (B) Paired G0/G1 samples from C.IL6/iMyc^Eμ mice (lanes 1-4 and lane 13) or C.IL6/iMyc^Cα mice (lanes 5-9 and 11-12). Lanes 10 and 14 contain samples from normal mice used as control. Paired G0 and G1 samples with shared M components are indicated by joined black boxes. M components only present in the G0 or G1 sample are indicated by white asterisks. The position of the γ protein band is indicated to the right and the anode/cathode to the left. C indicates serum from a control non–tumor-bearing mouse.