Plasma cell hyperplasia in young, tumor-free C.IL6/iMyc mice. (A) Low-power view of an abnormal accumulation of plasmablasts and plasma cells in an enlarged peripheral lymph node of a 4-week-old C.IL6/iMycCα mouse (H&E stain; original magnification, ×20; final magnification, ×50). The 3 areas indicated by squares are shown below at higher power (final magnification, ×100; B-D). The arrow in panel C denotes cell that is undergoing division.