Time to first or single episode of malaria and anemia stratified for β-globin genotypes. (A-B) Kaplan-Meier plots for failures of children between the age of 3 and 24 months (± 4 weeks). Solid line represents HbAA; dotted line, HbAS; and dashed line, HbAC. (A) Cumulative proportion of children with a first or single uncomplicated malaria episode. The difference between the group with HbAA genotype and the HbAS genotype was not significant (P < .08 by Breslow test). (B) Cumulative proportion of children with a first or single episode of anemia. The difference between the group with the HbAA genotype and the HbAS genotype was significant (P < .001 by Breslow test).