Genomic alterations per MPN patient in chronic versus blast phase. (A) Mean of SNP-array alterations per patient in MPN versus MPN-blast phase with (i) unmatched samples and (ii) matched samples (± SD); **P < .001. (B) Mean of SNP-array aberrations compared with cytogenetic alterations per patient in chronic versus blast phase with (i) unmatched samples and (ii) matched samples (± SD).