Survival analysis in MPN-blast phase. (A) Survival from the time of diagnosis of blast phase in transformed MPN patients with normal chromosome 7 (normal 7q) compared with either monosomy 7 (−7)/deletion of 7q (7q−) or 7qCNN-LOH. (B) Survival from the time of diagnosis of blast phase in transformed MPN patients with homozygous JAK2V617F⁺ associated with 9pCNN-LOH compared with either heterozygous JAK2V617F⁺ with 9p duplication/trisomy 9 or no abnormality, or patients without the mutation (JAK2 wild type). Median survival (months) and the case numbers for each group (transformed PV, ET, or PMF) are listed in supplemental Table 5.