Abnormal erythrocyte morphology. (A) Peripheral blood smears and scanning electron photomicrographs from control (NOD-+/+) and homozygous mutant (sph^3J/sph^3J) mice, and (B) control (B6-+/+) and homozygous mutant (sph^4J/sph^4J) mice. Bars, 10 μm. (C) RBC hemoglobin concentration (RBC HC) and volume distribution (RBC Vol) histograms.