Figure 5
![Figure 5. Readministration of AAV vectors by ATVRX in HB dogs previously exposed to AAV-2 vectors. (A-B) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs D32 (red) and B46 (black) upon readminstration of an AAV2-cFIX vector via ATVRX. (D-E) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs E59 (red) and H27 (black) upon readminstration of an AAV6-cFIX vector via ATVRX. (C,F) Creatinine phosphokinase (CPK) levels. x axis represents time in days.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/115/23/10.1182_blood-2009-12-261156/4/zh89991053360005.jpeg?Expires=1735497797&Signature=F1d6YYkwv28skDEoJ8FABFNDwO5emrwy6AyetocCGFAdiP8Hg0WkUqhkWR48nPdg2k9D6G7ruBYviQog0Gp4kAxU2H2VXIYHrJ1GLQWqBGCOnh0b3jmN--1i1U7FpgkSK6amB8wDU-Xg20hQ1U~UDMCz6cIgKqHka6M0Bz7qOy1~g7ENXxxXmBwg72T2CoaVesixgkqHMmT1R4jU8wXwpLhpkE62oinSFXJsq3f3UQNn98RV-aCxd29-nH2yfRi124cQI8SoClFZ3VGiOc49-1FdsKdSYdxVBDb7RRfeXII8xT8RvmDVcEVLVb~zclPpQz7S2-fnVVwovCBJhZ92zA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Readministration of AAV vectors by ATVRX in HB dogs previously exposed to AAV-2 vectors. (A-B) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs D32 (red) and B46 (black) upon readminstration of an AAV2-cFIX vector via ATVRX. (D-E) Canine FIX levels measured by ELISA and coagulation activity (WBCT in minutes [m]) in dogs E59 (red) and H27 (black) upon readminstration of an AAV6-cFIX vector via ATVRX. (C,F) Creatinine phosphokinase (CPK) levels. x axis represents time in days.
