Figure 2
Impaired CR by a potent TGase inhibitor cystamine. PRP of wild-type mice was incubated with 1 U/mL thrombin, 5mM CaCl2 at 37°C for 1 hour in the absence (left) or the presence of 1mM (middle) or 10mM (right) cystamine. The extent of CR was assessed at 60 minutes by measuring the clot weight. Data are mean ± SD of triplicates. *Statistically significant difference (P < .001) was observed between the absence versus the presence of cystamine.
