PKB induces membrane expression of integrins on hematopoietic progenitors. CD34⁺ cells were either retrovirally transduced with myrPKB or eGFP alone (A-B; n = 10 and 8, respectively) or cultured in presence of the PKB inhibitor VIII for 48 hours (C-D); n = 5 and 7, respectively). The expression levels of CD49d and CD18 were determined by flow cytometric analysis. (B,D) Data were depicted as fold induction compared with untransduced or untreated cells. PE indicates phycoerythrin. Error bars represent SEM. Samples significantly different (P < .05) are indicated with horizontal lines and asterisks.