Expression of active LFA-1 on DCs attenuates delayed-type hypersensitivity response. Ovalbumin-specific naive CD4⁺ OT-II T cells were transferred into wild-type (WT) syngeneic recipients, followed by a 2-fold injection of ovalbumin peptide–pulsed wild-type or LFA-1^d/d DCs into hind footpad 24 hours and 17 days after T-cell transfer. Twenty-four hours after the final DC transfer, footpad swelling was measured (n = 8 mice). *P < .05, **P < .01, #P < .001.