Impact of AZA/VPA pretreatment on MAGE-specific CTL recognition of a hematopoietic target. (A) IFN-γ production of generated CD8⁺ T-cell clone in response to the cell line JJN3 after exposure to control media, azacitidine (AZA) only, VPA only, or combined AZA/VPA. Values on the x-axis are calculated as a percentage of recognition, 100% being the amount of IFN-γ produced when peptide was loaded onto the cell line. (B) IFN-γ production of generated CD8⁺ T-cell clone in response to the cell line U266 after exposure to control media, AZA only, VPA only, or combined AZA/VPA. Values on the x-axis are calculated as a percentage of recognition, 100% being the amount of IFN-γ produced when peptide was loaded onto the cell line.