FeCl₃ thrombosis injury model in wild-type and TULA-dKO murine platelets. Wild-type and TULA-dKO mice were subjected to injury of the left carotid artery by 7.5% FeCl₃ for 2 minutes, and the time to occlusion and thrombus stability was noted. (A) Plot of time to occlusion for each group of mice; n = 12 for each group. Calculations were 16.5 ± 3 minutes for wild-type and 7.37 ± 0.76 minutes for TULA-dKO (mean ± SD). Statistical analysis was performed using an unpaired t test. (B) Plot of thrombus stability, defined as a complete occlusion for at least 5 minutes.