Random crawling in hpa-tg venules results in a decreased ability to clear bacterial infections. (A) Change in percentage of inoculated bacteria (bacterial bioluminescence) with time in WT (n = 9) and hpa-tg mice (n = 5), after subcutaneous administration of 10⁶ CFU of bioluminescent S aureus (strain Xen 29). *P < .05 vs WT. (B) Clearance rate of S aureus. (C) Representative images of S aureus bioluminescence detection in WT and hpa-tg mice at different time points after inoculation. Please note that the scales differ between time points but are the same at the same time point so that the mice can readily be compared.