Dendrogram and heatmap. Vertical dendrogram shows sample clustering with 5 major branches and 11 distinct clusters; the dendrogram is cut at 11 clusters. First column,11 clusters: CD2, CD-2 cluster; CD1, CD-1 cluster; CTA, CTA cluster; NFκB, NFκB cluster; NP, no clear profile; HY, HY cluster; PRL3, PRL3 cluster; PR, PR cluster; MF, MF cluster; MS, MS cluster; Myeloid, Myeloid cluster. Translocations are shown in the second column: t(11;14), yellow; t(4;14), blue; t(14;16) or t(14;20), red; no translocation, green; and not determined, white. The third column indicates hyperdiploidy: y, hyperdiploidy (yellow); n, no hyperdiploidy (green) and nd (not determined; white). Horizontal dendrogram shows clustering of genes. The heatmap shows the spectrum of expression values, the log2 expression value from the geometric mean for each gene is indicated by a color, with red representing positive expression (up-regulation) and blue representing negative expression (down-regulation) of a gene.