Poor-prognosis CLL patients exhibit short telomere length distributions. (A) XpYp STELA gels displaying the telomere length profiles in B cells from normal and CLL patients and MRC5 fibroblast cells entering crisis in culture after the expression of HPV E6E7.⁶  Binet staging is indicated above the CLL samples. PD is detailed above the MRC5 samples; mean and SD are detailed below. The mean for the MRC5 cells is for the shorter of the 2 XpYp telomeric alleles. At PD53, the short telomere has disappeared. (B-C) Scatter plots of mean length at the XpYp and 17p telomeres plotted against Binet.