Telomere length correlates with prognostic markers, and heterogeneity indicates clonal growth. (A-E) Scatter plots displaying mean length at the XpYp telomere plotted against (A) ZAP-70 expression, (B) VH gene sequence homology, (C) CD38 expression, (D) β₂-microglobulin, and (E) whether the patients had undergone treatment at the point of analysis. (F) Telomere length heterogeneity (SD) and clinical staging compared with heterogeneity of clonal fibroblast populations derived from a single cell. Student t test (2-tailed) was used for statistics.