Overall survival of systemic mastocytosis patients. Kaplan-Meier survival curves for SM patients per WHO subtype: indolent SM (ISM; red curve); aggressive SM (ASM; green curve); SM with AHNMD (AHD; yellow curve); and mast cell leukemia (MCL; purple curve). Survival of SM patients is compared with survival of age- and gender-matched US population (blue curve). Previously published in Blood.²