The expansion of Vδ2neg γδ T cells in patients with CMV reactivation during 3 to 12 months after SCT. (A) Expanded Vδ2neg γδ T cells were analyzed in patients divided into subgroups of patients with CMV reactivation (n = 6, ■) and patients without reactivation (n = 8, □). (B) Patients were divided according to CMV and EBV serology into CMV+/+ (n = 14, □), CMV−/− (n = 20, ), and CMV−/EBV+ (n = 14, ■). The median values of absolute numbers of Vδ2neg γδ T cells were plotted. Dashed line represents the median normal range generated from 45 healthy persons. Samples were analyzed using nonparametric Mann-Whitney test, and P values were determined. P values less than .05 were considered significant. (C) Frequencies of CD3+ Vδ2neg γδ T cells and CD8 effector CD28−CD57+ αβ T cells were determined in patients reactivating CMV (left panel) and in patients with no reactivation (right panel).