Hematopoietic cell engraftment and multilineage development in noninjected BM. The level of human CD45⁺ cells (A), CD19⁺ B cells (B), CD33⁺ myeloid cells (C), CD3⁺ T cells (D), CD45⁻GlyA⁺ erythroid cells (E), and CD34⁺ cells (F). Lineage engraftment (B-F) expressed as frequency of human CD45 cells. *P < .05, **P < .01 by Wilcoxon rank-sum test. ● represents experiment 1 females; ○, experiment 1 males; ■, experiment 2 females; and □, experiment 2 males. N = 5 to 7 per group.