Analysis of hematopoietic colony formation in RPS19R62W transgenic mice. (A) Analysis of CFU-GM, BFU-E, and CFU-E from individual day 13.5 fetal livers. Cells were plated in triplicate. The genotypes of the embryos appear below the bars. The Prion-Cre transgene alone = + Cre (□); the R62W transgene alone = Tg + (□); the R62W transgene plus Prion-Cre = Tg Cre (■). (B) Analysis of CFU-GM, BFU-E, and CFU-E from 4- to 6-week-old mice. The data are compiled from 4 to 6 individual mice; cells from each mouse were plated in duplicate. The genotypes of the embryos appear below the bars. The Prion-Cre transgene alone = + Cre (□); the R62W transgene plus Prion-Cre = Tg Cre (■).