Morphologic analysis of Wright-Giemsa-stained Lin⁻ bone marrow cells from R62W transgenic mice in the basophilic erythroblast (R3) and reticulocyte (R5) gates. The analysis was performed on a Nikon Eclipse TE300 microscope with a 40×/0.75 NA oil objective under Cargill Immersion oil (type 5). Images were taken with a Nikon N70 camera. No subsequent manipulations were performed. (Left) Analysis of cells from mice carrying the RPS19R62W transgene alone (RPS19R62W). (Right) Analysis of cells from mice carrying the RPS19R62W transgene and the Prion-Cre transgene (RPS19R62W; Cre). Note the binucleate cells among the RPS19R62W, Cre basophilic erythroblasts (R3), and the poorly hemoglobinized and nucleated cells among the RPS19R62W, Cre reticulocytes (R5).