Characterization of infectious peritonitis. Injecting GBS intraperitoneally to WT mice triggers an immediate (A) leukocytes infiltrate comprising (B) GR1-positive polymorphonuclear leukocytes (PMNs) and F4/80-positive macrophages as well as (C) CD3-positive T and CD19-positive B cells. Total peritoneal leukocytes were prepared for (D) COX1 and COX2 protein expression while (E) PGE₂, (F) prostacyclin, measured as its stable metabolites 6-keto PGF1α and 2,3-dinor 6-keto PGF_1α, (G) TNFα, and (H) IL-10 were determined in the cell-free inflammatory exudates. Values are expressed as the mean ± SEM of 5-12 mice/group.