Translocation of P2X1 and P2X4 receptors to the immune synapse of activated T cells. Time-lapse confocal live-cell microscopy images showing the expression of EGFP-tagged P2X1 (A) and P2X4 receptors (B) in Jurkat cells stimulated with anti-CD3/CD28 antibody-loaded beads (asterisks). Localization of receptors persists at least 1 hour after stimulation (Right panels: fluorescent microscopy images 60 minutes after stimulation).