Western blot analysis of select proteins induced in Daudi by the parental antibodies and HexAbs. Parent antibodies each at 133 nM (A,C-D) or 10nM (E); the HexAbs, each at 10nM (A-E); or anti-IgM, at 10 μg/mL (A,C). The changes in phospho-Lyn observed with 20-20, 22-20, and 20-22 within the first 24 hours are shown in panel B.