Acceleration of F-MuLV–induced erythroleukemia progression in SHIP-1 deficient mice. (A) Mean survival rate of F-MuLV–infected Balb/c mice. SHIP-1^−/− n = 11; SHIP-1^+/− n = 25; SHIP-1^+/+ n = 21. (B) The survival rate of mice infected with F-MuLV as presented by a Kaplan-Meier survival curve. (C) Fli-1 and SHIP-1 protein expression in the spleens of 8-week-old SHIP-1^−/− and SHIP-1^+/− F-MuLV-induced erythroleukemic mice. (D) Mean hematocrit levels of 8-week-old mice infected with F-MuLV. (E) Mean RBC counts of 8-week-old mice infected with F-MuLV. (F) Mean hemoglobin levels in 8-week-old mice infected with F-MuLV. (D-F) n = 3.