Figure 6
![Figure 6. Time course of reversal from pulmonary protection after cessation of ATL146e. NY1DD mice were treated with ATL146e (10 ng/kg/minute, 3 days osmotic pump). Pulmonary parameters were measured on days 3, 4, and 7 after the cessation of ATL146e infusion. All parameters measured (vascular permeability [EBD], breathing measurements [TV, FOB], and pulmonary cell infiltrates) returned toward NY1DD baseline levels on day 4, 1 day after the cessation of ATL146e treatment, and returned to baseline levels by day 7. The solid and dashed lines represent the mean ± SEM of breathing parameters in C57BL/6 mice. Data were analyzed by 1-way ANOVA with Neuman-Keuls posttesting. *P < .05.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/116/23/10.1182_blood-2010-06-290643/4/zh89991061350006.jpeg?Expires=1735814630&Signature=U9vAuDJsO37wRCx2dJ7~mBeDAuV6~jNz2x-W9GZtHxJcJ2Inq~tb1mfTP58okPykMxUt7mvMJ4sNjr8v8PyjkrWArUCFYnSb6S0e7FMrHSQZVHSeEdLjhWtqjWd6~zXGIGsyCtZ82uVa05Q30Q7JdDfqdGxSaZTnFlOnScdQnL4I~qI9LHJb-EFqW~ba5LCTICyZHHiw4G1Mr2J0E0YLUiYaXLzHMdAdg2SWZMfymMUNC2i03kftwoTknvsaobqHdzxxD6Mko2Lvl0RVAELzS~abxjq6eYgI-TH71SwxO-UXNbGykKKXM8iFu10C5Yw82RacH5sGuN9hNOfHbA8NFg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Time course of reversal from pulmonary protection after cessation of ATL146e. NY1DD mice were treated with ATL146e (10 ng/kg/minute, 3 days osmotic pump). Pulmonary parameters were measured on days 3, 4, and 7 after the cessation of ATL146e infusion. All parameters measured (vascular permeability [EBD], breathing measurements [TV, FOB], and pulmonary cell infiltrates) returned toward NY1DD baseline levels on day 4, 1 day after the cessation of ATL146e treatment, and returned to baseline levels by day 7. The solid and dashed lines represent the mean ± SEM of breathing parameters in C57BL/6 mice. Data were analyzed by 1-way ANOVA with Neuman-Keuls posttesting. *P < .05.
