PPAR-γ activation inhibits the hDectin-1–induced secretion of inflammatory cytokines and chemokines. mDCs were generated in the presence of the PPAR-γ ligand TGZ or DMSO as a control, and stimulated with curdlan on day 6 of culture. Cytokine and chemokine secretion in the culture supernatants was determined 24 hours later using ELISA. The data shown are representative of at least 3 independent experiments.