Trib1 and Trib2, but not Trib3, induce AML. (A) Kaplan-Meier survival curve of mice receiving BM transplant with Trib1 (n = 11), Trib2 (n = 6), Trib3 (n = 14), or control MigR1 (n = 9) transduced cells. Results are derived from 2 independent experiments. (B) Average survival for indicated BM transplantation. P values determined by Student t test are indicated. NS indicates no significant difference. The difference between Trib1 and Trib2 yielded P > .1 (Student t test). (C) Average splenic weight and white blood cell count of MigR1, Trib1, Trib2, and Trib3 mice. *The splenic weights and white blood cell counts for the Trib2 mice are published.⁸  (D) Wright-Giemsa stain of BM cytospin from mice receiving the indicated BM transplantation.