VWF haplotypes constructed using the Haploview program. The haplotypes were constructed using the default setting that (1) ignores pairwise comparisons of markers more than 500 kb apart, (2) excludes persons with more than 50% of missing genotypes, (3) examines haplotypes found 1% or more in the population, (4) removes markers with Hardy-Weinberg disequilibrium, and (5) uses R² to define haplotype blocks. The majority of them are found in 9 LD blocks that distributed throughout the entire VWF gene.