Effect of NK314 on tumor growth of MT-1 cells transplanted into SCID mice. MT-1 cells were injected into the dorsal flank of SCID mice after 4 Gy irradiation. NK-314 at a dose of 10 mg/kg (▴) or 20 mg/kg (×), or phosphate-buffered saline (●), was injected intraperitoneally at days 14, 28, and 42 after inoculation (arrows). Tumor volume was calculated as (short axis)2 × (long axis)/2.