The Δ122p53 allele is associated with nonmalignant proliferative pathologies and inflammation. The 8 most common additional pathologies found with the Δ122p53 allele are listed with their corresponding frequencies compared with other genotypes. Pathologies were identified from hematoxylin and eosin-stained tissue sections. (A) Additional pathologies in the tumor cohorts from Figure 5. Mice that developed DLBCLs and DLBCL-like lymphomas are not included. (B) Additional pathologies in mice killed before tumor development (5-7 weeks old: Δ122p53, p53^−/Δ122p53, and p53^−/−; 7-10 months old: p53^+/Δ122p53 and p53^+/−); female mice in the breeding cohort that developed luteoma were killed. Results were from 20 Δ122p53, 10 p53^−/Δ122p53, 20 p53^−/−, 30 p53^+/Δ122p53, and 20 p53^+/− mice. (C) Photomicrographs of hematoxylin and eosin-stained sections show lymphocyte aggregations in the lung and liver present in Δ122p53 mice. Magnifications are indicated. Photomicrographs were taken with a Zeiss Axioplan Universal Microscope with 10×/0.3 and 20×/0.8 objective lenses. Images were captured using a SPOT Camera (SP 6.0) and Software Version 4.6.1. Images were cropped using Photoshop Version CS2 (Adobe).