CD45 is required for protection from MCMV infection. Survival of DAP12-deficient neonatal mice given 1 × 105 Ly49H+ WT NK cells, CD45-deficient NK cells, or PBS and infected with 2 × 103 PFU of MCMV. P values were determined using the Mantel-Cox test. Data were combined from 2 separate experiments with each experiment giving similar results.