In situ follicular lymphoma and mantle cell lymphoma. (A) Lymph node with a reactive appearance. (B) BCL2 staining shows strong positive cells in some germinal centers (arrows) but not in others (arrowheads). (C) Lymphoid follicle with reactive appearance. (D) Cyclin D1 staining highlights a corona of positive cells in the mantle area. Photographic images were acquired with a Nikon Eclipse 50i microscope equipped with an Olympus (Olympus America Inc) DP71 camera and software. Final image preparation was performed with Adobe Photoshop CS4 extended Version 11.0.2. Original magnifications as follows: panel A(20×/0.1 NA); panel B (20×/0.1 NA); panel C (200×/0.75 NA); panel D (200×/0.75 NA).