Survival and weight changes of BALB/c recipients transplanted with donor C57BL/6 TCD BM cells with or without sorted, total, naive, or memory phenotype CD8+ T cells. (A,C) Survival of lethally irradiated BALB/c hosts given 2 × 106 TCD BM cells from donors with or without 1.0 × 106 naive T cells, 1.0 × 106 memory T cells, 0.5 × 106 naive T cells, 0.5 × 106 memory T cells, or 0.5 × 106 total CD8+ donor T cells (n = 8-11) is shown. The data were pooled from 2 independent experiments. (B,D) Percentage of starting body weight of host mice given TCD BM with or without sorted naive, memory, or total CD8+ T cells as in panels A and C. Brackets show SEM.