NF-kB DNA-binding analysis in DLBCL cell lines and primary samples. Statistical comparison of each NF-kB component DNA-binding activity in GCB versus ABC DLBCL cell lines (A) and DLBCL primary cells (B) were assessed by the Student t test of average value from the ELISA data in supplemental Figure 2A and B. P < .05 was considered statistically significant. (C) Six possible NF-kB dimer ratios obtained from the ELISA data in supplemental Figure 2A and B for DLBCL cell lines and primary samples, respectively, were compared in GCB versus ABC DLBCL subtypes by the Student t test. P < .05 was considered statistically significant.