GO-203 is effective in inhibiting growth of AML cells. (A) Amino acid sequences of GO-202, GO-203, and CP-3. MOLM-14 cells were left untreated (♦), and treated with 5μM GO-203 (■) or 5μM CP-2 (▵) each day for the indicated days. Viable cell number was determined by trypan blue exclusion. (B) MV4–11 cells were left untreated (♦), and treated with 5μM GO-203 (■) or 5μM CP-2 (▵) each day for the indicated days. Viable cell number was determined by trypan blue exclusion. (C) AML patient 1 cells were incubated with a control IgG or anti–MUC1-N (MAb DF3) and analyzed by flow cytometry. The percentage of MUC1-positive cells is indicated in the panels. (D) AML patient 1 cells were left untreated (♦), and treated with 5μM GO-203 (■) or 5μM CP-2 (▵) each day for the indicated days. Viable cell number was determined by trypan blue exclusion.