Histochemical analysis of wild-type and hepatocyte-deleted Mfrn1 livers. Livers from mice fed ALA were harvested at 6 weeks and stained with hematoxylin and eosin (A) or trichrome (B) in Alb-Cre;Mfrn1^+/+. (C) Enlarged image from panel B. Alb-Cre;Mfrn1^flox/+ were stained with hematoxylin and eosin (D) or trichrome (E). Panel F is an enlarged image from panel E. Alb-Cre;Mfrnl^flox/− were stained with hematoxylin and eosin (G) or trichrome (H). Panel I is an enlarged image from panel G. Asterisks in the enlarged images of panels F and I denote areas of fibrosis.