Over-expression of miR-125b changes the transcriptional profile of genes related to granulocytic differentiation. Transcriptional profiling of (A) myeloid transcription factors and (B) primary and secondary granule components in 32D/miR-ctrl cells (left panels compare G-CSF vs IL-3 conditions), 32D/miR-125b cells (middle panels compare G-CSF vs IL-3 conditions), and the fold difference between 32D/miR-ctrl and 32D/miR-125b cells in the presence of G-CSF (right panels compare 32D/miR-125b vs 32D/miR-ctrl) at the indicated time intervals. Hprt served as an endogenous control. Mean of 4 experiments is shown. *P < .05 compared with corresponding control at indicated time point of treatment.