Expression patterns of inhibitory receptors vary across distinct memory CD8⁺ T-cell subsets. Pooled data showing the percentage of CD8⁺ T cells expressing PD-1, CD160, 2B4, and LAG-3 within the total CD8⁺ T-cell pool from healthy donors (n = 19) and HIV⁺ persons before and after ART (n = 85). PD-1⁺, CD160⁺, 2B4⁺, and LAG-3⁺ expression in naive and memory CD8⁺ T-cell subsets from healthy donors and HIV⁺ persons before and after ART is also shown. Horizontal lines indicate median values. The P values were calculated using a combination of a paired test for the pre- and post-initiation of therapy measurements, and Mann-Whitney unpaired test to compare the HIV-negative group with HIV⁺ pre-ART of measures. *P < .01, **P < .001, ***P < .0001.