Role of KIR2DS1 in killing of allogeneic iDCs, mDCs, or PHA blasts by NKG2A⁺KIR2DS1⁺ NK-cell clones. The cytolytic activity of NKG2A⁺KIR2DS1⁺ NK-cell clones (derived from the C1/C1 Bw4/Bw4 donor P61) was analyzed against iDCs, mDCs, and PHA blasts derived from the C2/C2 Bw4/Bw4 donor RB either in the absence or in the presence of mAb to the indicated molecules. The E:T ratio used against iDCs and mDCs was 15:1 whereas that used against PHA blasts was 20:1. Average of 3 independent experiments and SD (mean ± SD) are indicated.