A CpG-loaded, whole-cell vaccine generates robust antitumor immunity. (A) Vaccination schema: C57BL/6 donors were vaccinated with either CpG/H11 or H11. (B) Cohorts of C57BL/6 recipient mice (n = 10) and (C) TLR9KO (C57BL/6 background) recipient mice were followed for tumor growth and survival. Numbers in parentheses represent the number of mice that survived more than 100 days. Results are representative of 2 independent experiments.