Homozygous loss region analysis. A representative homozygous loss region of case 2 is shown (1p12-p13.1). The total scale of the figure is approximately 2 Mb. The arrowhead indicates a homozygous loss region; arrows indicate heterozygous loss regions. Homozygous loss was found only in the PB sample. The log2 ratio of this region in the LN sample was slightly lower than that in the neighboring regions, suggesting the possibility that a minor subclone may exist in the LNs.