Expression levels of the mRNA-miRNA pairs. The box plots represent the expression levels of miRNAs and mRNA in hyper-reactive platelets (Hyper) and hyporeactive (Hypo) platelets. (A) The hsa-miR-200b (left) and PRKAR2B mRNA (right) pair. (B) The hsa-miR-495 (left) and KLHL5 mRNA (right) pair. (C) The hsa-miR-107 (left) and CLOCK mRNA (right) pair. In each pair, the directionality of the Hyper versus Hypo group is opposite for the miRNA and the mRNA. Notably, all miRNAs and mRNAs are significantly differentially expressed (P < .05) between the Hyper and Hypo groups.