The anemia of Ndfip1^−/− mice under iron-deficient conditions is partly contributable to inflammation. (A) IL-6 and (B) TNF-α are increased in Ndfip1^−/− mice compared with Ndfip1^+/+ mice fed a low-iron diet but are not significantly different on the normal diet. (C) WBC count is significantly increased in Ndfip1^−/− mice compared with Ndfip1^+/+ mice fed both the low-iron and normal diet. These factors are indicative of anemia of inflammation. nd, not detected. Data represent mean ± SD, *P < .05, n = 3-7.