Viremia, normocytic anemia, thrombocytopenia, leukocytosis, and severe weight loss in EBV-infected NOG-hCD34 mice. (A) EBV load in the PB of 3 representative EBV-infected mice. (B-I) Longitudinal analyses of hematopoietic cells in PB. PB was routinely collected from mock-infected and EBV-infected mice, and the numbers of erythrocytes (B), platelets (C), and leukocytes (I) were measured by hematometry. Hematocrit (D), hemoglobin concentration (E), and the values of MCV (F), MCH (G), and MCHC (H) were also measured by hematometry. (J) Change on body weight. The body weights of mock-infected and EBV-infected mice were routinely measured and are shown as the ratio to the initial weight. Results from mock-infected mice (n = 7) are presented in means ± SEM, and representative results of 3 EBV-infected mice are, respectively shown. Each color represents the result from an identical EBV-infected mouse.