Chromosomal regions affected in patients with AP and BP. The left pie diagram shows proportion of patients with chromosome aberrations detected by standard metaphase cytogenetics (MC) [only Philadelphia chromosome (Ph; white), unbalanced (black), balanced (light gray), and both classes of abnormalities (dark gray)] in persons with AP and BP (N = 40), whereas the right pie chart represents the abnormalities by SNP-A karyotyping [normal (white) or abnormal (black); N = 26].