Phenotypic analysis of female mice according to their Bmp6/Tmprss6 genotypes. The phenotypes analyzed include hepcidin mRNA expression relative to β-actin (A), nonheme iron concentration of liver (B), plasmatic iron (C), and Id1 mRNA expression relative to β-actin (D). Data are presented as mean ± SD. *P < .05 compared with Bmp6^+/+Tmprss6^+/+controls; **P < .05 compared with Bmp6^−/−Tmprss6^+/+ mice; ***P < .05 compared with Bmp6^+/+Tmprss6^−/− mice.