MYC represses BLIMP1α in transformed and untransformed GC B cells. (A) Representative Western blot for MYC and β-actin after the transfection of primary human GC B cells with MYC expression vector or control. (B) Quantitative RT-PCR for BLIMP1α in GC B cells after ectopic MYC expression (one representative experiment of 3 is shown). (C) RNAi-mediated knockdown of MYC in BL2 and DG75 BL lines using smartpool siRNA targeting MYC or scrambled control siRNA. (D) MYC knockdown led to the up-regulation of BLIMP1α in both BL lines.