Hematopoietic differentiation potential of BM- and CB-derived iPSCs. (A) In coculture with OP9, blood-derived iPSCs generate a CD34⁺ population of cells with typical subsets including CD43⁺ hematopoietic progenitors, CD31⁺CD43⁻ endothelial cells, and CD31⁻CD43⁻ mesenchymal cells. The CD43⁺ population of hematopoietic cells consists of CD235a⁺CD41a^+/− erythro-megakaryocytic progenitors and CD235a/CD41a⁻CD45^+/− multipotent progenitors. The representative experiment shows hematopoietic subsets generated from the BM iPSC1 line. (B) Percentage of CD43⁺ hematopoietic cells generated from hESC H1, fibroblast (DF), and blood-derived (BM, CB) iPSC lines after 8 days of coculture with OP9.